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Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease

INTRODUCTION: Dysfunction of the cerebral vasculature is considered one of the key components of Alzheimer’s disease (AD), but the mechanisms affecting individual brain vessels are poorly understood. METHODS: Here, using in vivo two-photon microscopy in superficial cortical layers and ex vivo imagin...

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Detalles Bibliográficos
Autores principales: Zhukov, Oleg, He, Chen, Soylu-Kucharz, Rana, Cai, Changsi, Lauritzen, Andreas D., Aldana, Blanca Irene, Björkqvist, Maria, Lauritzen, Martin, Kucharz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228387/
https://www.ncbi.nlm.nih.gov/pubmed/37261266
http://dx.doi.org/10.3389/fnagi.2023.1089005