Cargando…
Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen
There are no effective treatment options for most patients with metastatic colorectal cancer (mCRC). mCRC remains a leading cause of tumor-related death, with a five-year survival rate of only 15%, highlighting the urgent need for novel pharmacological products. Current standard drugs are based on c...
Autores principales: | Plüss, Louis, Peissert, Frederik, Elsayed, Abdullah, Rotta, Giulia, Römer, Jonas, Dakhel Plaza, Sheila, Villa, Alessandra, Puca, Emanuele, De Luca, Roberto, Oxenius, Annette, Neri, Dario |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228411/ https://www.ncbi.nlm.nih.gov/pubmed/37243574 http://dx.doi.org/10.1080/19420862.2023.2217964 |
Ejemplares similares
-
Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties
por: Elsayed, Abdullah, et al.
Publicado: (2023) -
Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology
por: Peissert, Frederik, et al.
Publicado: (2023) -
A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis
por: Murer, Patrizia, et al.
Publicado: (2020) -
Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade
por: Dakhel, Sheila, et al.
Publicado: (2019) -
An Attenuated Targeted-TNF Localizes to Tumors In Vivo and Regains Activity at the Site of Disease
por: Dakhel, Sheila, et al.
Publicado: (2021)