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Atazanavir-induced unconjugated hyperbilirubinemia prevents vascular hyporeactivity during experimental human endotoxemia

OBJECTIVE: Inflammation-induced free radical release is important in the pathogenesis of several diseases, including atherosclerosis and sepsis. Heme oxygenase (HO) breaks down heme into carbon monoxide, iron, and biliverdin. Biliverdin IXα is directly converted to bilirubin by biliverdin reductase....

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Detalles Bibliográficos
Autores principales:	Dorresteijn, Mirrin J., Dekker, Douwe, Zwaag, Jelle, Heemskerk, Suzanne, Roelofs, Hennie M.J., Smits, Paul, van der Hoeven, Johannes G., Wagener, Frank A.D.T.G., Pickkers, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228648/ https://www.ncbi.nlm.nih.gov/pubmed/37261364 http://dx.doi.org/10.3389/fimmu.2023.1176775

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