Itaconate family-based host-directed therapeutics for infections

Itaconate is a crucial anti-infective and anti-inflammatory immunometabolite that accumulates upon disruption of the Krebs cycle in effector macrophages undergoing inflammatory stress. Esterified derivatives of itaconate (4-octyl itaconate and dimethyl itaconate) and its isomers (mesaconate and citr...

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Detalles Bibliográficos
Autores principales: Yuk, Jae-Min, Park, Eun-Jin, Kim, In Soo, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228716/
https://www.ncbi.nlm.nih.gov/pubmed/37261340
http://dx.doi.org/10.3389/fimmu.2023.1203756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228716/
https://www.ncbi.nlm.nih.gov/pubmed/37261340
http://dx.doi.org/10.3389/fimmu.2023.1203756

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