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Macrophages induce gingival destruction via Piezo1-mediated MMPs-degrading collagens in periodontitis

Macrophages are an integral part of the innate immune response in periodontal tissue and play a crucial role in the progression of periodontitis. Here we reported that macrophages also provoke periodontitis-induced gingival destruction through Piezol-mediated collagen degradation. We discovered that...

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Detalles Bibliográficos
Autores principales: Zhao, Tong, Chu, Zhuangzhuang, Chu, Catherine Huihan, Dong, Shuo, Li, Guoqing, Wu, Jin, Tang, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228731/
https://www.ncbi.nlm.nih.gov/pubmed/37261355
http://dx.doi.org/10.3389/fimmu.2023.1194662