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Identification of curaxin as a potential new therapeutic for JAK2 V617F mutant patients
Myelofibrosis is a myeloproliferative neoplasm (MPN) which typically results in reduced length and quality of life due to systemic symptoms and blood count changes arising from fibrotic changes in the bone marrow. While the JAK2 inhibitor ruxolitinib provides some clinical benefit, there remains a s...
Autores principales: | Pearson, Stella, Blance, Rognvald, Yan, Fei, Hsieh, Ya-Ching, Geary, Bethany, Amaral, Fabio M. R., Somervaille, Tim C. P., Kirschner, Kristina, Whetton, Anthony D., Pierce, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228771/ https://www.ncbi.nlm.nih.gov/pubmed/37253035 http://dx.doi.org/10.1371/journal.pone.0286412 |
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