Cargando…
Identification of CDRH3 loops in the B cell receptor repertoire that can be engaged by candidate immunogens
A major goal for the development of vaccines against rapidly mutating viruses, such as influenza or HIV, is to elicit antibodies with broad neutralization capacity. However, B cell precursors capable of maturing into broadly neutralizing antibodies (bnAbs) can be rare in the immune repertoire. Due t...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228794/ https://www.ncbi.nlm.nih.gov/pubmed/37196027 http://dx.doi.org/10.1371/journal.ppat.1011401 |