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Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center
PURPOSE: This study was performed to determine the demographic profile and clinical characteristics in patients with Fuchs’ endothelial corneal dystrophy (FECD) reporting to a tertiary eye care center in India. It is a retrospective, single-center, observational study. METHODS: The study included 28...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228915/ https://www.ncbi.nlm.nih.gov/pubmed/36727349 http://dx.doi.org/10.4103/ijo.IJO_1288_22 |
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author | Bhadra, Pratik Sahoo, Sonali Sahu, Srikant K Priyadarshini, Smrutirekha Mohanty, Amrita Das, Sujata |
author_facet | Bhadra, Pratik Sahoo, Sonali Sahu, Srikant K Priyadarshini, Smrutirekha Mohanty, Amrita Das, Sujata |
author_sort | Bhadra, Pratik |
collection | PubMed |
description | PURPOSE: This study was performed to determine the demographic profile and clinical characteristics in patients with Fuchs’ endothelial corneal dystrophy (FECD) reporting to a tertiary eye care center in India. It is a retrospective, single-center, observational study. METHODS: The study included 280 patients (559 eyes) diagnosed with FECD presenting between January 2013 and December 2020. The data was collected from the electronic medical record system of the institute. Patient data included demographic features, clinical characteristics, investigations, and surgical interventions. RESULTS: The mean age of the patients was 62 years. Late-onset FECD (95.7%) was more common than early-onset FECD (4.3%). Male: female ratio for late-onset FECD and early-onset FECD was 1:1.65 and 3:1, respectively. More than one-third of the patients had associated systemic history. Preexisting ocular diseases were seen in 5.9% of eyes. Blurring of vision was seen in 383 eyes (68.5%), 13 eyes (2.1%) had glare, and 163 eyes (29.2%) were asymptomatic. A total of 113 surgical interventions were done in 108 eyes (including repeat transplants). Only cataract surgery was done in 40 (7.2%) eyes, whereas penetrating keratoplasty, Descemet stripping endothelial keratoplasty, and Descemet membrane endothelial keratoplasty without or with cataract surgery (sequential or triple procedure) were done in 12 (2.1%), 47 (8.4%), and 14 (2.5%) eyes, respectively. CONCLUSION: Patients with FECD present mostly during the sixth decade. Posterior lamellar keratoplasty is the most common transplant procedure being performed on FECD patients. |
format | Online Article Text |
id | pubmed-10228915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-102289152023-05-31 Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center Bhadra, Pratik Sahoo, Sonali Sahu, Srikant K Priyadarshini, Smrutirekha Mohanty, Amrita Das, Sujata Indian J Ophthalmol Original Article PURPOSE: This study was performed to determine the demographic profile and clinical characteristics in patients with Fuchs’ endothelial corneal dystrophy (FECD) reporting to a tertiary eye care center in India. It is a retrospective, single-center, observational study. METHODS: The study included 280 patients (559 eyes) diagnosed with FECD presenting between January 2013 and December 2020. The data was collected from the electronic medical record system of the institute. Patient data included demographic features, clinical characteristics, investigations, and surgical interventions. RESULTS: The mean age of the patients was 62 years. Late-onset FECD (95.7%) was more common than early-onset FECD (4.3%). Male: female ratio for late-onset FECD and early-onset FECD was 1:1.65 and 3:1, respectively. More than one-third of the patients had associated systemic history. Preexisting ocular diseases were seen in 5.9% of eyes. Blurring of vision was seen in 383 eyes (68.5%), 13 eyes (2.1%) had glare, and 163 eyes (29.2%) were asymptomatic. A total of 113 surgical interventions were done in 108 eyes (including repeat transplants). Only cataract surgery was done in 40 (7.2%) eyes, whereas penetrating keratoplasty, Descemet stripping endothelial keratoplasty, and Descemet membrane endothelial keratoplasty without or with cataract surgery (sequential or triple procedure) were done in 12 (2.1%), 47 (8.4%), and 14 (2.5%) eyes, respectively. CONCLUSION: Patients with FECD present mostly during the sixth decade. Posterior lamellar keratoplasty is the most common transplant procedure being performed on FECD patients. Wolters Kluwer - Medknow 2023-02 2023-02-02 /pmc/articles/PMC10228915/ /pubmed/36727349 http://dx.doi.org/10.4103/ijo.IJO_1288_22 Text en Copyright: © 2023 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Bhadra, Pratik Sahoo, Sonali Sahu, Srikant K Priyadarshini, Smrutirekha Mohanty, Amrita Das, Sujata Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title | Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title_full | Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title_fullStr | Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title_full_unstemmed | Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title_short | Demographic profile and clinical characteristics of Fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
title_sort | demographic profile and clinical characteristics of fuchs’ endothelial corneal dystrophy in a tertiary eye care center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228915/ https://www.ncbi.nlm.nih.gov/pubmed/36727349 http://dx.doi.org/10.4103/ijo.IJO_1288_22 |
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