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Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity

BACKGROUND: Dysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus disease 2019 (COVID-19) to severe disease. We sought to determine whether early host immune-related gene expression could predict...

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Detalles Bibliográficos
Autores principales: MacCann, Rachel, Leon, Alejandro Abner Garcia, Gonzalez, Gabriel, Carr, Michael J., Feeney, Eoin R., Yousif, Obada, Cotter, Aoife G., de Barra, Eoghan, Sadlier, Corinna, Doran, Peter, Mallon, Patrick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229044/
https://www.ncbi.nlm.nih.gov/pubmed/37261339
http://dx.doi.org/10.3389/fimmu.2023.1166574