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Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity

BACKGROUND: Dysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus disease 2019 (COVID-19) to severe disease. We sought to determine whether early host immune-related gene expression could predict...

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Detalles Bibliográficos
Autores principales:	MacCann, Rachel, Leon, Alejandro Abner Garcia, Gonzalez, Gabriel, Carr, Michael J., Feeney, Eoin R., Yousif, Obada, Cotter, Aoife G., de Barra, Eoghan, Sadlier, Corinna, Doran, Peter, Mallon, Patrick W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229044/ https://www.ncbi.nlm.nih.gov/pubmed/37261339 http://dx.doi.org/10.3389/fimmu.2023.1166574

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