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Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho

Beta klotho (KLB) is a fundamental component in fibroblast growth factor receptor (FGFR) signaling as it serves as an obligatory coreceptor for the endocrine hormones fibroblast growth factor 19 (FGF19) and fibroblast growth factor 21 (FGF21). Through the development of FGF19- and FGF21 mimetics, KL...

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Detalles Bibliográficos
Autores principales: Aaldijk, Alexandra S., Verzijl, Cristy R. C., Jonker, Johan W., Struik, Dicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229096/
https://www.ncbi.nlm.nih.gov/pubmed/37260446
http://dx.doi.org/10.3389/fendo.2023.1150222