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Deep reinforcement learning for data-driven adaptive scanning in ptychography

We present a method that lowers the dose required for an electron ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed method is built upon a deep learning model that is trai...

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Autores principales: Schloz, Marcel, Müller, Johannes, Pekin, Thomas C., Van den Broek, Wouter, Madsen, Jacob, Susi, Toma, Koch, Christoph T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229550/
https://www.ncbi.nlm.nih.gov/pubmed/37253763
http://dx.doi.org/10.1038/s41598-023-35740-1
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author Schloz, Marcel
Müller, Johannes
Pekin, Thomas C.
Van den Broek, Wouter
Madsen, Jacob
Susi, Toma
Koch, Christoph T.
author_facet Schloz, Marcel
Müller, Johannes
Pekin, Thomas C.
Van den Broek, Wouter
Madsen, Jacob
Susi, Toma
Koch, Christoph T.
author_sort Schloz, Marcel
collection PubMed
description We present a method that lowers the dose required for an electron ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed method is built upon a deep learning model that is trained by reinforcement learning, using prior knowledge of the specimen structure from training data sets. We show that using adaptive scanning for electron ptychography outperforms alternative low-dose ptychography experiments in terms of reconstruction resolution and quality.
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spelling pubmed-102295502023-06-01 Deep reinforcement learning for data-driven adaptive scanning in ptychography Schloz, Marcel Müller, Johannes Pekin, Thomas C. Van den Broek, Wouter Madsen, Jacob Susi, Toma Koch, Christoph T. Sci Rep Article We present a method that lowers the dose required for an electron ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed method is built upon a deep learning model that is trained by reinforcement learning, using prior knowledge of the specimen structure from training data sets. We show that using adaptive scanning for electron ptychography outperforms alternative low-dose ptychography experiments in terms of reconstruction resolution and quality. Nature Publishing Group UK 2023-05-30 /pmc/articles/PMC10229550/ /pubmed/37253763 http://dx.doi.org/10.1038/s41598-023-35740-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Schloz, Marcel
Müller, Johannes
Pekin, Thomas C.
Van den Broek, Wouter
Madsen, Jacob
Susi, Toma
Koch, Christoph T.
Deep reinforcement learning for data-driven adaptive scanning in ptychography
title Deep reinforcement learning for data-driven adaptive scanning in ptychography
title_full Deep reinforcement learning for data-driven adaptive scanning in ptychography
title_fullStr Deep reinforcement learning for data-driven adaptive scanning in ptychography
title_full_unstemmed Deep reinforcement learning for data-driven adaptive scanning in ptychography
title_short Deep reinforcement learning for data-driven adaptive scanning in ptychography
title_sort deep reinforcement learning for data-driven adaptive scanning in ptychography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229550/
https://www.ncbi.nlm.nih.gov/pubmed/37253763
http://dx.doi.org/10.1038/s41598-023-35740-1
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