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Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo

The spatial sorting of RNA transcripts is fundamental for the refinement of gene expression to distinct subcellular regions. Although, in non-mammalian early embryogenesis, differential RNA localisation presages cell fate determination, in mammals it remains unclear. Here, we uncover apical-to-basal...

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Detalles Bibliográficos
Autores principales: Hawdon, Azelle, Geoghegan, Niall D., Mohenska, Monika, Elsenhans, Anja, Ferguson, Charles, Polo, Jose M., Parton, Robert G., Zenker, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229589/
https://www.ncbi.nlm.nih.gov/pubmed/37253716
http://dx.doi.org/10.1038/s41467-023-38436-2