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Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications. Here, we describe an assembly-line approach to build AVVs by engineering the well-characterized structural components of bacteriophage T4. S...

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Detalles Bibliográficos
Autores principales:	Zhu, Jingen, Batra, Himanshu, Ananthaswamy, Neeti, Mahalingam, Marthandan, Tao, Pan, Wu, Xiaorong, Guo, Wenzheng, Fokine, Andrei, Rao, Venigalla B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229621/ https://www.ncbi.nlm.nih.gov/pubmed/37253769 http://dx.doi.org/10.1038/s41467-023-38364-1

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