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The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score

BACKGROUND: Identification of reliable risk-stratification tools is critical for surgical decision making, particularly in frail and elderly. The aim of the study is to validate the Emergency Surgery Frailty Index (EmSFI), in over 65 years old patients operated on for acute appendicitis. METHODS: An...

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Autores principales: Fusario, Daniele, Neri, Alessandro, Carbone, Ludovico, Resca, Luca, Marano, Luigi, Gassi, Giulia, Calomino, Natale, Verre, Luigi, Roviello, Franco, Marrelli, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229705/
https://www.ncbi.nlm.nih.gov/pubmed/36947203
http://dx.doi.org/10.1007/s00268-023-06975-w
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author Fusario, Daniele
Neri, Alessandro
Carbone, Ludovico
Resca, Luca
Marano, Luigi
Gassi, Giulia
Calomino, Natale
Verre, Luigi
Roviello, Franco
Marrelli, Daniele
author_facet Fusario, Daniele
Neri, Alessandro
Carbone, Ludovico
Resca, Luca
Marano, Luigi
Gassi, Giulia
Calomino, Natale
Verre, Luigi
Roviello, Franco
Marrelli, Daniele
author_sort Fusario, Daniele
collection PubMed
description BACKGROUND: Identification of reliable risk-stratification tools is critical for surgical decision making, particularly in frail and elderly. The aim of the study is to validate the Emergency Surgery Frailty Index (EmSFI), in over 65 years old patients operated on for acute appendicitis. METHODS: An observational study was conducted enrolling elderly patients with diagnosis of acute appendicitis who underwent emergency appendicectomy or right colectomy, between 2016 and 2021. All patients were treated according to the last SIFIPAC/WSES/SICG/SIMEU guidelines. RESULTS: Overall, 61 patients were analyzed. Complication rate was higher for patients in the second EmSFI risk Class. Moreover, ROC analyses identified 3 as the best cutoff value in predicting risk of adverse postoperative events. Complication rate was higher in oldest elderly patients—over 80 years—(42.9 vs 22.5%; p 0.05) and was mainly related to medical complications (42.9 vs 12.5%, p 0.007). However, intestinal obstruction, peri-appendicular abscess on preoperative CT, peritonitis and a longer duration of surgery are related with increased risk of complications in the group of patients under 80 years. CONCLUSION: The EmSFI score results a valid prognostic marker for frailty status, and it may support the surgeon in emergency setting for acute appendicitis. Patients aged 80 years or older have a higher risk of complications, independent from those factors which relate to increased morbidity in younger elderly patients. Age alone is not a reliable indicator of the real surgical risk, but it must encourage the adoption of multidisciplinary collaborative models of care for this group of patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00268-023-06975-w.
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spelling pubmed-102297052023-06-01 The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score Fusario, Daniele Neri, Alessandro Carbone, Ludovico Resca, Luca Marano, Luigi Gassi, Giulia Calomino, Natale Verre, Luigi Roviello, Franco Marrelli, Daniele World J Surg Original Scientific Report BACKGROUND: Identification of reliable risk-stratification tools is critical for surgical decision making, particularly in frail and elderly. The aim of the study is to validate the Emergency Surgery Frailty Index (EmSFI), in over 65 years old patients operated on for acute appendicitis. METHODS: An observational study was conducted enrolling elderly patients with diagnosis of acute appendicitis who underwent emergency appendicectomy or right colectomy, between 2016 and 2021. All patients were treated according to the last SIFIPAC/WSES/SICG/SIMEU guidelines. RESULTS: Overall, 61 patients were analyzed. Complication rate was higher for patients in the second EmSFI risk Class. Moreover, ROC analyses identified 3 as the best cutoff value in predicting risk of adverse postoperative events. Complication rate was higher in oldest elderly patients—over 80 years—(42.9 vs 22.5%; p 0.05) and was mainly related to medical complications (42.9 vs 12.5%, p 0.007). However, intestinal obstruction, peri-appendicular abscess on preoperative CT, peritonitis and a longer duration of surgery are related with increased risk of complications in the group of patients under 80 years. CONCLUSION: The EmSFI score results a valid prognostic marker for frailty status, and it may support the surgeon in emergency setting for acute appendicitis. Patients aged 80 years or older have a higher risk of complications, independent from those factors which relate to increased morbidity in younger elderly patients. Age alone is not a reliable indicator of the real surgical risk, but it must encourage the adoption of multidisciplinary collaborative models of care for this group of patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00268-023-06975-w. Springer International Publishing 2023-03-22 2023 /pmc/articles/PMC10229705/ /pubmed/36947203 http://dx.doi.org/10.1007/s00268-023-06975-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Scientific Report
Fusario, Daniele
Neri, Alessandro
Carbone, Ludovico
Resca, Luca
Marano, Luigi
Gassi, Giulia
Calomino, Natale
Verre, Luigi
Roviello, Franco
Marrelli, Daniele
The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title_full The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title_fullStr The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title_full_unstemmed The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title_short The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score
title_sort emergency surgery frailty index (emsfi) in elderly patients with acute appendicitis: an external validation of prognostic score
topic Original Scientific Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229705/
https://www.ncbi.nlm.nih.gov/pubmed/36947203
http://dx.doi.org/10.1007/s00268-023-06975-w
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