Tau-dependent HDAC1 nuclear reduction is associated with altered VGluT1 expression

During AD pathology, Tau protein levels progressively increase from early pathological stages. Tau altered expression causes an unbalance of Tau subcellular localization in the cytosol and in the nuclear compartment leading to synaptic dysfunction, neuronal cell death and neurodegeneration as a cons...

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Detalles Bibliográficos
Autores principales: Siano, Giacomo, Madaro, Giuseppe, Caiazza, Maria Claudia, Allouch, Awatef, Varisco, Martina, Mignanelli, Marianna, Cattaneo, Antonino, Di Primio, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229822/
https://www.ncbi.nlm.nih.gov/pubmed/37266450
http://dx.doi.org/10.3389/fcell.2023.1151223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229822/
https://www.ncbi.nlm.nih.gov/pubmed/37266450
http://dx.doi.org/10.3389/fcell.2023.1151223

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