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Tau-dependent HDAC1 nuclear reduction is associated with altered VGluT1 expression
During AD pathology, Tau protein levels progressively increase from early pathological stages. Tau altered expression causes an unbalance of Tau subcellular localization in the cytosol and in the nuclear compartment leading to synaptic dysfunction, neuronal cell death and neurodegeneration as a cons...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229822/ https://www.ncbi.nlm.nih.gov/pubmed/37266450 http://dx.doi.org/10.3389/fcell.2023.1151223 |