New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project

Current test strategies to identify thyroid hormone (TH) system disruptors are inadequate for conducting robust chemical risk assessment required for regulation. The tests rely heavily on histopathological changes in rodent thyroid glands or measuring changes in systemic TH levels, but they lack spe...

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Detalles Bibliográficos
Autores principales: Ramhøj, Louise, Axelstad, Marta, Baert, Yoni, Cañas-Portilla, Ana I., Chalmel, Frédéric, Dahmen, Lars, De La Vieja, Antonio, Evrard, Bertrand, Haigis, Ann-Cathrin, Hamers, Timo, Heikamp, Kim, Holbech, Henrik, Iglesias-Hernandez, Patricia, Knapen, Dries, Marchandise, Lorna, Morthorst, Jane E., Nikolov, Nikolai Georgiev, Nissen, Ana C. V. E., Oelgeschlaeger, Michael, Renko, Kostja, Rogiers, Vera, Schüürmann, Gerrit, Stinckens, Evelyn, Stub, Mette H., Torres-Ruiz, Monica, Van Duursen, Majorie, Vanhaecke, Tamara, Vergauwen, Lucia, Wedebye, Eva Bay, Svingen, Terje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229837/
https://www.ncbi.nlm.nih.gov/pubmed/37265663
http://dx.doi.org/10.3389/ftox.2023.1189303

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