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Sex and Estrous Cycle Are Not Mediators of S-Ketamine’s Rapid-Antidepressant Behavioral Effects in a Genetic Rat Model of Depression

BACKGROUND: Recent preclinical and clinical studies have shed light on the possible impact of sex and estrous/menstrual cycle on ketamine’s antidepressant action but with incongruous results. The preclinical studies that have shown the effects of ovarian sex hormones have not done so in animal model...

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Detalles Bibliográficos
Autores principales: Arjmand, Shokouh, Vadstrup Pedersen, Marie, Silva, Nicole R, Landau, Anne M, Joca, Sâmia, Wegener, Gregers
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229850/
https://www.ncbi.nlm.nih.gov/pubmed/37067203
http://dx.doi.org/10.1093/ijnp/pyad016