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IGF-1 Microinjection in the Prefrontal Cortex Attenuates Fentanyl-Seeking Behavior in Mice

BACKGROUND: Opioid use disorder (OUD) is a chronic relapsing psychiatric disorder with an enormous socioeconomic burden. Opioid overdose deaths have reached an epidemic level, especially for fentanyl. One of the biggest challenges to treat OUD is the relapse to drug seeking after prolonged abstinenc...

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Detalles Bibliográficos
Autores principales:	Li, Guohui, Yue, Shuwen, Wang, Yunwanbin, Singh, Archana, Wang, Zi-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Regular Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229852/ https://www.ncbi.nlm.nih.gov/pubmed/36951642 http://dx.doi.org/10.1093/ijnp/pyad013

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