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Shifting the balance: soluble ADAM10 as a potential treatment for Alzheimer's disease
INTRODUCTION: Accumulation of amyloid β in the brain is regarded as a key initiator of Alzheimer's disease pathology. Processing of the amyloid precursor protein (APP) in the amyloidogenic pathway yields neurotoxic amyloid β species. In the non-amyloidogenic pathway, APP is processed by membran...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229884/ https://www.ncbi.nlm.nih.gov/pubmed/37266401 http://dx.doi.org/10.3389/fnagi.2023.1171123 |