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A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents

PURPOSE: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. METHODS: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care cent...

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Autores principales: Morya, Arvind Kumar, Kaur, Kirandeep, Gurnani, Bharat, Janti, Siddharam S, Shrivastava, Ankur Kumar, Tejaswini, Antarvedi, Sinha, Aprajita, Venkatesh, Dharavath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229984/
https://www.ncbi.nlm.nih.gov/pubmed/36872683
http://dx.doi.org/10.4103/IJO.IJO_2567_22
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author Morya, Arvind Kumar
Kaur, Kirandeep
Gurnani, Bharat
Janti, Siddharam S
Shrivastava, Ankur Kumar
Tejaswini, Antarvedi
Sinha, Aprajita
Venkatesh, Dharavath
author_facet Morya, Arvind Kumar
Kaur, Kirandeep
Gurnani, Bharat
Janti, Siddharam S
Shrivastava, Ankur Kumar
Tejaswini, Antarvedi
Sinha, Aprajita
Venkatesh, Dharavath
author_sort Morya, Arvind Kumar
collection PubMed
description PURPOSE: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. METHODS: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care center from January 2021 to August 2022. Twenty-three eyes of 21 anisomyopic and isomyopic amblyopia patients operated for posterior chamber phakic IOL (Eyecryl phakic IOL) as a treatment for amblyopia were included in the study. Patient demographics, pre- and postoperative visual acuity, cycloplegic refraction, anterior and posterior segment examination, intraocular pressure, pachymetry, contrast sensitivity, endothelial count, and patient satisfaction scores were evaluated. Patients were followed up at day 1, 6 weeks, 3 months, and 1 year after surgery, and visual outcomes and complications were documented. RESULTS: The mean age of patients was 14.16 ± 3.49 years (range: 10–19 years). The mean intraocular lens power was − 12.20 diopter spherical (DS) in 23 eyes and − 2.25 diopter cylindrical (DC) in four patients. The mean unaided distant visual acuity (UDVA) and best-corrected visual acuity (BCVA) were 1.39 ± 0.25 and 0.40 ± 0.21 preoperatively on the log of minimum angle of resolution (logMAR) chart. Postoperatively, the visual acuity improved by 2.6 lines in 3 months period and maintained till 1 year. Postsurgery, contrast sensitivity in the amblyopic eyes significantly improved, and the average endothelial loss recorded was 5.78% at 1 year, which was statistically insignificant. Patient satisfaction score was statistically significant, with 4.736/5 recorded on the Likert scale. CONCLUSION: Posterior chamber phakic IOL is a safe, effective, and alternative method for treating amblyopia patients who are noncompliant with glasses, contact lenses, and keratorefractive procedures.
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spelling pubmed-102299842023-06-01 A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents Morya, Arvind Kumar Kaur, Kirandeep Gurnani, Bharat Janti, Siddharam S Shrivastava, Ankur Kumar Tejaswini, Antarvedi Sinha, Aprajita Venkatesh, Dharavath Indian J Ophthalmol Original Article PURPOSE: To analyze the demographics and clinical outcomes of posterior chamber phakic intraocular (IOL) implantation for refractive amblyopia in children and adolescents. METHODS: A prospective interventional study was performed on children and adolescents with amblyopia at a tertiary eye care center from January 2021 to August 2022. Twenty-three eyes of 21 anisomyopic and isomyopic amblyopia patients operated for posterior chamber phakic IOL (Eyecryl phakic IOL) as a treatment for amblyopia were included in the study. Patient demographics, pre- and postoperative visual acuity, cycloplegic refraction, anterior and posterior segment examination, intraocular pressure, pachymetry, contrast sensitivity, endothelial count, and patient satisfaction scores were evaluated. Patients were followed up at day 1, 6 weeks, 3 months, and 1 year after surgery, and visual outcomes and complications were documented. RESULTS: The mean age of patients was 14.16 ± 3.49 years (range: 10–19 years). The mean intraocular lens power was − 12.20 diopter spherical (DS) in 23 eyes and − 2.25 diopter cylindrical (DC) in four patients. The mean unaided distant visual acuity (UDVA) and best-corrected visual acuity (BCVA) were 1.39 ± 0.25 and 0.40 ± 0.21 preoperatively on the log of minimum angle of resolution (logMAR) chart. Postoperatively, the visual acuity improved by 2.6 lines in 3 months period and maintained till 1 year. Postsurgery, contrast sensitivity in the amblyopic eyes significantly improved, and the average endothelial loss recorded was 5.78% at 1 year, which was statistically insignificant. Patient satisfaction score was statistically significant, with 4.736/5 recorded on the Likert scale. CONCLUSION: Posterior chamber phakic IOL is a safe, effective, and alternative method for treating amblyopia patients who are noncompliant with glasses, contact lenses, and keratorefractive procedures. Wolters Kluwer - Medknow 2023-03 2023-03-03 /pmc/articles/PMC10229984/ /pubmed/36872683 http://dx.doi.org/10.4103/IJO.IJO_2567_22 Text en Copyright: © 2023 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Morya, Arvind Kumar
Kaur, Kirandeep
Gurnani, Bharat
Janti, Siddharam S
Shrivastava, Ankur Kumar
Tejaswini, Antarvedi
Sinha, Aprajita
Venkatesh, Dharavath
A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_full A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_fullStr A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_full_unstemmed A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_short A clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
title_sort clinical trial on phakic intraocular lens for the treatment of refractive amblyopia in children and adolescents
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229984/
https://www.ncbi.nlm.nih.gov/pubmed/36872683
http://dx.doi.org/10.4103/IJO.IJO_2567_22
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