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Human gut microbiome: A primer for the clinician
The human host gets tremendously influenced by a genetically and phenotypically distinct and heterogeneous constellation of microbial species—the human microbiome—the gut being one of the most densely populated and characterized site for these organisms. Microbiome science has advanced rapidly, tech...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230107/ https://www.ncbi.nlm.nih.gov/pubmed/37265934 http://dx.doi.org/10.1002/jgh3.12902 |
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author | Kedia, Saurabh Ahuja, Vineet |
author_facet | Kedia, Saurabh Ahuja, Vineet |
author_sort | Kedia, Saurabh |
collection | PubMed |
description | The human host gets tremendously influenced by a genetically and phenotypically distinct and heterogeneous constellation of microbial species—the human microbiome—the gut being one of the most densely populated and characterized site for these organisms. Microbiome science has advanced rapidly, technically with respect to the analytical methods and biologically with respect to its mechanistic influence in health and disease states. A clinician conducting a microbiome study should be aware of the nuances related to microbiome research, especially with respect to the technical and biological factors that can influence the interpretation of research outcomes. Hence, this review is an attempt to detail these aspects of the human gut microbiome, with emphasis on its determinants in a healthy state. |
format | Online Article Text |
id | pubmed-10230107 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-102301072023-06-01 Human gut microbiome: A primer for the clinician Kedia, Saurabh Ahuja, Vineet JGH Open Review Article The human host gets tremendously influenced by a genetically and phenotypically distinct and heterogeneous constellation of microbial species—the human microbiome—the gut being one of the most densely populated and characterized site for these organisms. Microbiome science has advanced rapidly, technically with respect to the analytical methods and biologically with respect to its mechanistic influence in health and disease states. A clinician conducting a microbiome study should be aware of the nuances related to microbiome research, especially with respect to the technical and biological factors that can influence the interpretation of research outcomes. Hence, this review is an attempt to detail these aspects of the human gut microbiome, with emphasis on its determinants in a healthy state. Wiley Publishing Asia Pty Ltd 2023-05-24 /pmc/articles/PMC10230107/ /pubmed/37265934 http://dx.doi.org/10.1002/jgh3.12902 Text en © 2023 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Review Article Kedia, Saurabh Ahuja, Vineet Human gut microbiome: A primer for the clinician |
title | Human gut microbiome: A primer for the clinician |
title_full | Human gut microbiome: A primer for the clinician |
title_fullStr | Human gut microbiome: A primer for the clinician |
title_full_unstemmed | Human gut microbiome: A primer for the clinician |
title_short | Human gut microbiome: A primer for the clinician |
title_sort | human gut microbiome: a primer for the clinician |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230107/ https://www.ncbi.nlm.nih.gov/pubmed/37265934 http://dx.doi.org/10.1002/jgh3.12902 |
work_keys_str_mv | AT kediasaurabh humangutmicrobiomeaprimerfortheclinician AT ahujavineet humangutmicrobiomeaprimerfortheclinician |