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Somatic genetic alterations predict hematological progression in GATA2 deficiency

Germline GATA2 mutations predispose to myeloid malignancies resulting from the progressive acquisition of additional somatic mutations. Here we describe clinical and biological features of 78 GATA2-deficient patients. Hematopoietic stem and progenitor cell phenotypic characterization revealed an exh...

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Detalles Bibliográficos
Autores principales:	Largeaud, Laetitia, Collin, Matthew, Monselet, Nils, Vergez, François, Fregona, Vincent, Larcher, Lise, Hirsch, Pierre, Duployez, Nicolas, Bidet, Audrey, Luquet, Isabelle, Bustamante, Jacinta, Dufrechou, Stéphanie, Prade, Naïs, Nolla, Marie, Hamelle, Camille, Tavitian, Suzanne, Habib, Christophe, Meynier, Mateo, Bellanné-Chantelot, Christine, Donadieu, Jean, de Fontbrune, Flore Sicre, Fieschi, Claire, Ferster, Alina, Delhommeau, François, Delabesse, Eric, Pasquet, Marlène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2023
Materias:	Article - Bone Marrow Failure
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230419/ https://www.ncbi.nlm.nih.gov/pubmed/36727400 http://dx.doi.org/10.3324/haematol.2022.282250

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