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Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Metformin can enhance cancer cell chemosensitivity to anticancer drugs. IGF-1R is involved in cancer chemoresistance. The current study aimed to elucidate the role of metformin in osteosarcoma (OS) cell chemosensitivity modulation and identify its underlying mechanism in IGF-1R/miR-610/FEN1 signalli...

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Detalles Bibliográficos
Autores principales: Dong, Suwei, Xiao, Yanbin, Zhu, Ziqiang, Ma, Xiang, Peng, Zhuohui, Kang, Jianping, Wang, Jianqiang, Wang, Yunqing, Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230554/
https://www.ncbi.nlm.nih.gov/pubmed/37195011
http://dx.doi.org/10.4081/ejh.2023.3612