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Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway
Metformin can enhance cancer cell chemosensitivity to anticancer drugs. IGF-1R is involved in cancer chemoresistance. The current study aimed to elucidate the role of metformin in osteosarcoma (OS) cell chemosensitivity modulation and identify its underlying mechanism in IGF-1R/miR-610/FEN1 signalli...
Autores principales: | Dong, Suwei, Xiao, Yanbin, Zhu, Ziqiang, Ma, Xiang, Peng, Zhuohui, Kang, Jianping, Wang, Jianqiang, Wang, Yunqing, Li, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230554/ https://www.ncbi.nlm.nih.gov/pubmed/37195011 http://dx.doi.org/10.4081/ejh.2023.3612 |
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