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Plasmodium 18S Ribosomal RNA Biomarker Clearance After Food and Drug Administration–Approved Antimalarial Treatment in Controlled Human Malaria Infection Trials

BACKGROUND: Sensitive molecular assays, such as quantitative reverse-transcription polymerase chain reaction (qRT-PCR) of Plasmodium 18S ribosomal RNA (rRNA), are increasingly the primary method of detecting infections in controlled human malaria infection (CHMI) trials. However, thick blood smears...

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Detalles Bibliográficos
Autores principales:	Chavtur, Chris, Staubus, Weston J, Ho, Mabel, Hergott, Dianna E B, Seilie, Annette M, Healy, Sara, Duffy, Patrick, Jackson, Lisa, Talley, Angela, Kappe, Stefan H I, Hoffman, Stephen L, Richie, Thomas L, Kublin, James G, Chang, Ming, Murphy, Sean C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230565/ https://www.ncbi.nlm.nih.gov/pubmed/37265668 http://dx.doi.org/10.1093/ofid/ofad202

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