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Arginine-Glycine-Aspartic Acid-anchored Curcumin-based Nanotherapeutics Inhibit Pyroptosis-induced Cytokine Release Syndrome for In Vivo and In Vitro Sepsis Applications

AIM: We aimed to design RGD-anchored liposomes encapsulating an antipyroptosis drug that could efficiently target macrophages and relieve the rate of cytokine release syndrome, providing a new strategy for sepsis treatment, especially sepsis-induced acute renal injury. BACKGROUND: Sepsis is a clinic...

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Detalles Bibliográficos
Autores principales:	Shi, Yi, Wu, Qian, Lu, Yi, Meng, Ling-Peng, Xu, Xiao-Ling, Wang, Xiao-Juan, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2023
Materias:	Medicine, Immunology, Inflammation & Allergy, Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230609/ https://www.ncbi.nlm.nih.gov/pubmed/36722481 http://dx.doi.org/10.2174/1381612829666230201144029

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