Inferring cell-type-specific causal gene regulatory networks during human neurogenesis

BACKGROUND: Genetic variation influences both chromatin accessibility, assessed in chromatin accessibility quantitative trait loci (caQTL) studies, and gene expression, assessed in expression QTL (eQTL) studies. Genetic variants can impact either nearby genes (cis-eQTLs) or distal genes (trans-eQTLs...

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Detalles Bibliográficos
Autores principales: Aygün, Nil, Liang, Dan, Crouse, Wesley L., Keele, Gregory R., Love, Michael I., Stein, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230710/
https://www.ncbi.nlm.nih.gov/pubmed/37254169
http://dx.doi.org/10.1186/s13059-023-02959-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230710/
https://www.ncbi.nlm.nih.gov/pubmed/37254169
http://dx.doi.org/10.1186/s13059-023-02959-0

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