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Single-cell RNA sequencing reveals the mediatory role of cancer-associated fibroblast PTN in hepatitis B virus cirrhosis-HCC progression

BACKGROUND: Cancer-associated fibroblasts (CAFs) are essential stromal components in the tumor microenvironment of hepatocellular carcinoma (HCC). Hepatitis B virus (HBV) infection induces pathological changes such as liver fibrosis/cirrhosis and HCC. The aim of this research was to explore the nove...

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Detalles Bibliográficos
Autores principales: Lin, Chenhong, Chen, Yeda, Zhang, Feng, Zhu, Peng, Yu, Liangliang, Chen, Wenbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230711/
https://www.ncbi.nlm.nih.gov/pubmed/37259127
http://dx.doi.org/10.1186/s13099-023-00554-z