Analysis of the microglia transcriptome across the human lifespan using single cell RNA sequencing

BACKGROUND: Microglia are tissue resident macrophages with a wide range of critically important functions in central nervous system development and homeostasis. METHOD: In this study, we aimed to characterize the transcriptional landscape of ex vivo human microglia across different developmental age...

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Detalles Bibliográficos
Autores principales: Yaqubi, Moein, Groh, Adam M. R., Dorion, Marie-France, Afanasiev, Elia, Luo, Julia Xiao Xuan, Hashemi, Hadi, Sinha, Sarthak, Kieran, Nicholas W., Blain, Manon, Cui, Qiao-Ling, Biernaskie, Jeff, Srour, Myriam, Dudley, Roy, Hall, Jeffery A., Sonnen, Joshua A., Arbour, Nathalie, Prat, Alexandre, Stratton, Jo Anne, Antel, Jack, Healy, Luke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230780/
https://www.ncbi.nlm.nih.gov/pubmed/37254100
http://dx.doi.org/10.1186/s12974-023-02809-7

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