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Causality of genetically determined metabolites and metabolic pathways on osteoarthritis: a two-sample mendelian randomization study
BACKGROUND: Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases and is the leading cause of pain and disability in the aged population. However, the underlying biological mechanism has not been fully understood. This study aims to reveal the causal effect of circulation metabol...
Autores principales: | Gu, Yifei, Jin, Qianmei, Hu, Jinquan, Wang, Xinwei, Yu, Wenchao, Wang, Zhanchao, Wang, Chen, Liu, Yang, Chen, Yu, Yuan, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230782/ https://www.ncbi.nlm.nih.gov/pubmed/37259122 http://dx.doi.org/10.1186/s12967-023-04165-9 |
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