Evidence for a lack of inotropic and chronotropic effects of glucagon and glucagon receptors in the human heart

BACKGROUND: Glucagon is thought to increase heart rate and contractility by stimulating glucagon receptors and increasing 3′,5′-cyclic adenosine monophosphate (cAMP) production in the myocardium. This has been confirmed in animal studies but not in the human heart. The cardiostimulatory effects of g...

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Detalles Bibliográficos
Autores principales: Aranda-Domene, Ramón, Orenes-Piñero, Esteban, Arribas-Leal, José María, Canovas-Lopez, Sergio, Hernández-Cascales, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230788/
https://www.ncbi.nlm.nih.gov/pubmed/37254135
http://dx.doi.org/10.1186/s12933-023-01859-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230788/
https://www.ncbi.nlm.nih.gov/pubmed/37254135
http://dx.doi.org/10.1186/s12933-023-01859-8

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