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Obstacles to the deceased donor transplantation in Pakistan
INTRODUCTION: Transplantation in many Asian countries is moulded by socioeconomic, religious, cultural and health indicators. In most Asian countries, the living-related donation is the common most organ donation. Due to the limited deceased organ donation, live donor programmes flourished in many A...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230924/ https://www.ncbi.nlm.nih.gov/pubmed/37253533 http://dx.doi.org/10.1136/bmjgast-2022-001101 |
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author | Ullah, Kaleem Dogar, Abdul Wahab Ochani, Sidhant Shoaib, Azam Shah, Hussain Haider Ur Rehman, Mohammad Ebad |
author_facet | Ullah, Kaleem Dogar, Abdul Wahab Ochani, Sidhant Shoaib, Azam Shah, Hussain Haider Ur Rehman, Mohammad Ebad |
author_sort | Ullah, Kaleem |
collection | PubMed |
description | INTRODUCTION: Transplantation in many Asian countries is moulded by socioeconomic, religious, cultural and health indicators. In most Asian countries, the living-related donation is the common most organ donation. Due to the limited deceased organ donation, live donor programmes flourished in many Asian countries. Another apparent reason for this tremendous growth of living-related programmes in Asian countries is their larger serving population. Several centres from Asia, including Pakistan and India from Southeast Asia and Egypt in Middle East Asia, on the one hand, have recently emerged as leading living donor transplant programmes. On the other hand, a few Asian countries, including Iran and China, have established some of the world’s largest deceased donor programmes. DISCUSSION: In Pakistan, thousands of patients die from end-stage organ failure annually, seeking organ transplants for survival. The exact statics are not available, but over 50 000 people are estimated to die each year as a result of end-stage organ failure without getting a transplant, about 15 000–18 000 from kidney failure, and 10 000 from liver failure and the National Centre for Health Statistics labelled organ failure as a leading cause of death. Despite all these efforts, the knowledge of organ donation among Pakistani people was determined to be around 60%. In Pakistan, the lack of deceased organ donation programmes and the unwillingness of people to deceased organ donation contributes to an increased demand for living organ donation and patients continue to rely on living donors. We discuss various obstacles to deceased organ donation comprising various challenges that form a unique combination, including religious, economic, social, demographic and political factors. Conclusion: Every single effort should be made to initiate and establish multiple deceased donor programmes in Pakistan. Developing the deceased donor programmes in the country will be vital to counter the countrywide increasing organ shortage. The mainstay transplant activities like organ procurement and distribution systems need to be adequately developed. It will help achieve national self-sufficiency and decrease living donors’ burden. With education, the behaviour of healthcare professionals and common people can be changed and a positive attitude toward deceased organ donation can be obtained. As healthcare professionals, we should come forward and take responsibility by enrolling ourselves in deceased donors’ registration. Public awareness, medical community interest and government support are essential in initiating and establishing deceased donor programmes in Pakistan. |
format | Online Article Text |
id | pubmed-10230924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-102309242023-06-01 Obstacles to the deceased donor transplantation in Pakistan Ullah, Kaleem Dogar, Abdul Wahab Ochani, Sidhant Shoaib, Azam Shah, Hussain Haider Ur Rehman, Mohammad Ebad BMJ Open Gastroenterol Hepatology INTRODUCTION: Transplantation in many Asian countries is moulded by socioeconomic, religious, cultural and health indicators. In most Asian countries, the living-related donation is the common most organ donation. Due to the limited deceased organ donation, live donor programmes flourished in many Asian countries. Another apparent reason for this tremendous growth of living-related programmes in Asian countries is their larger serving population. Several centres from Asia, including Pakistan and India from Southeast Asia and Egypt in Middle East Asia, on the one hand, have recently emerged as leading living donor transplant programmes. On the other hand, a few Asian countries, including Iran and China, have established some of the world’s largest deceased donor programmes. DISCUSSION: In Pakistan, thousands of patients die from end-stage organ failure annually, seeking organ transplants for survival. The exact statics are not available, but over 50 000 people are estimated to die each year as a result of end-stage organ failure without getting a transplant, about 15 000–18 000 from kidney failure, and 10 000 from liver failure and the National Centre for Health Statistics labelled organ failure as a leading cause of death. Despite all these efforts, the knowledge of organ donation among Pakistani people was determined to be around 60%. In Pakistan, the lack of deceased organ donation programmes and the unwillingness of people to deceased organ donation contributes to an increased demand for living organ donation and patients continue to rely on living donors. We discuss various obstacles to deceased organ donation comprising various challenges that form a unique combination, including religious, economic, social, demographic and political factors. Conclusion: Every single effort should be made to initiate and establish multiple deceased donor programmes in Pakistan. Developing the deceased donor programmes in the country will be vital to counter the countrywide increasing organ shortage. The mainstay transplant activities like organ procurement and distribution systems need to be adequately developed. It will help achieve national self-sufficiency and decrease living donors’ burden. With education, the behaviour of healthcare professionals and common people can be changed and a positive attitude toward deceased organ donation can be obtained. As healthcare professionals, we should come forward and take responsibility by enrolling ourselves in deceased donors’ registration. Public awareness, medical community interest and government support are essential in initiating and establishing deceased donor programmes in Pakistan. BMJ Publishing Group 2023-05-30 /pmc/articles/PMC10230924/ /pubmed/37253533 http://dx.doi.org/10.1136/bmjgast-2022-001101 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Hepatology Ullah, Kaleem Dogar, Abdul Wahab Ochani, Sidhant Shoaib, Azam Shah, Hussain Haider Ur Rehman, Mohammad Ebad Obstacles to the deceased donor transplantation in Pakistan |
title | Obstacles to the deceased donor transplantation in Pakistan |
title_full | Obstacles to the deceased donor transplantation in Pakistan |
title_fullStr | Obstacles to the deceased donor transplantation in Pakistan |
title_full_unstemmed | Obstacles to the deceased donor transplantation in Pakistan |
title_short | Obstacles to the deceased donor transplantation in Pakistan |
title_sort | obstacles to the deceased donor transplantation in pakistan |
topic | Hepatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230924/ https://www.ncbi.nlm.nih.gov/pubmed/37253533 http://dx.doi.org/10.1136/bmjgast-2022-001101 |
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