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HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes

Herpes simplex virus 1 (HSV-1) infection exerts a profound shutoff of host gene expression at multiple levels. Recently, HSV-1 infection was reported to also impact promoter-proximal RNA polymerase II (Pol II) pausing, a key step in the eukaryotic transcription cycle, with decreased and increased Po...

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Detalles Bibliográficos
Autores principales: Weiß, Elena, Hennig, Thomas, Graßl, Pilar, Djakovic, Lara, Whisnant, Adam W., Jürges, Christopher S., Koller, Franziska, Kluge, Michael, Erhard, Florian, Dölken, Lars, Friedel, Caroline C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231138/
https://www.ncbi.nlm.nih.gov/pubmed/37093003
http://dx.doi.org/10.1128/jvi.00381-23