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A focus on aromaticity: fuzzier than ever before?

The field of aromaticity has grown five-fold in the last two decades as revealed by Merino et al. in their Perspective “Aromaticity: Quo Vadis” where they ask where the field is heading (Chem. Sci., 2023, https://doi.org/10.1039/D2SC04998H). Numerous computational tools for aromaticity analysis have...

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Autor principal: Ottosson, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231423/
https://www.ncbi.nlm.nih.gov/pubmed/37265718
http://dx.doi.org/10.1039/d3sc90075d
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author Ottosson, Henrik
author_facet Ottosson, Henrik
author_sort Ottosson, Henrik
collection PubMed
description The field of aromaticity has grown five-fold in the last two decades as revealed by Merino et al. in their Perspective “Aromaticity: Quo Vadis” where they ask where the field is heading (Chem. Sci., 2023, https://doi.org/10.1039/D2SC04998H). Numerous computational tools for aromaticity analysis have been introduced and novel classes of molecules that exhibit aromatic (or antiaromatic) features have been explored experimentally. Hence, the aromaticity concept is broader and possibly fuzzier than ever. Yet, earlier it also triggered vigorous debates after periods when new analysis tools emerged, and it survived. Today's debate reveals that the field is vital and that new knowledge is produced. Yet, as much as we ask where the field is moving, we should ask “Aromaticity: Cui Bono?”; who utilizes the aromaticity concept and who benefits from it? Especially, who benefits from it being overly fuzzy and who does the opposite? It is an exciting debate. We should get out of it with a better understanding of the chemical-bonding phenomenon labelled aromaticity.
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spelling pubmed-102314232023-06-01 A focus on aromaticity: fuzzier than ever before? Ottosson, Henrik Chem Sci Chemistry The field of aromaticity has grown five-fold in the last two decades as revealed by Merino et al. in their Perspective “Aromaticity: Quo Vadis” where they ask where the field is heading (Chem. Sci., 2023, https://doi.org/10.1039/D2SC04998H). Numerous computational tools for aromaticity analysis have been introduced and novel classes of molecules that exhibit aromatic (or antiaromatic) features have been explored experimentally. Hence, the aromaticity concept is broader and possibly fuzzier than ever. Yet, earlier it also triggered vigorous debates after periods when new analysis tools emerged, and it survived. Today's debate reveals that the field is vital and that new knowledge is produced. Yet, as much as we ask where the field is moving, we should ask “Aromaticity: Cui Bono?”; who utilizes the aromaticity concept and who benefits from it? Especially, who benefits from it being overly fuzzy and who does the opposite? It is an exciting debate. We should get out of it with a better understanding of the chemical-bonding phenomenon labelled aromaticity. The Royal Society of Chemistry 2023-05-23 /pmc/articles/PMC10231423/ /pubmed/37265718 http://dx.doi.org/10.1039/d3sc90075d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Ottosson, Henrik
A focus on aromaticity: fuzzier than ever before?
title A focus on aromaticity: fuzzier than ever before?
title_full A focus on aromaticity: fuzzier than ever before?
title_fullStr A focus on aromaticity: fuzzier than ever before?
title_full_unstemmed A focus on aromaticity: fuzzier than ever before?
title_short A focus on aromaticity: fuzzier than ever before?
title_sort focus on aromaticity: fuzzier than ever before?
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231423/
https://www.ncbi.nlm.nih.gov/pubmed/37265718
http://dx.doi.org/10.1039/d3sc90075d
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