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Trimethylaluminum-mediated one-pot peptide elongation

Efficient and straightforward peptide bond formation of N-, and C-terminal unprotected amino acids was successfully achieved by using trimethylaluminum. The coupling reaction was accomplished by pre-reaction of N-, and C-terminal unprotected amino acids and trimethylaluminum to form a five-membered...

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Detalles Bibliográficos
Autores principales: Hattori, Tomohiro, Yamamoto, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231425/
https://www.ncbi.nlm.nih.gov/pubmed/37265739
http://dx.doi.org/10.1039/d3sc00208j