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Dengue Fever in a Neonate: A Case Report

Dengue is one of the most common viral infections affecting the general population in endemic areas annually. However, it is barely reported in newborns owing to a widespread belief that they are protected from severe viral infections in the first six months of life by the presence of maternal antib...

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Autores principales: Bhattarai, Chaitanya Darshan, Yadav, Birendra Kumar, Basnet, Rabin, Karki, Manish, Chauhan, Shanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231546/
https://www.ncbi.nlm.nih.gov/pubmed/37203936
http://dx.doi.org/10.31729/jnma.8099
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author Bhattarai, Chaitanya Darshan
Yadav, Birendra Kumar
Basnet, Rabin
Karki, Manish
Chauhan, Shanta
author_facet Bhattarai, Chaitanya Darshan
Yadav, Birendra Kumar
Basnet, Rabin
Karki, Manish
Chauhan, Shanta
author_sort Bhattarai, Chaitanya Darshan
collection PubMed
description Dengue is one of the most common viral infections affecting the general population in endemic areas annually. However, it is barely reported in newborns owing to a widespread belief that they are protected from severe viral infections in the first six months of life by the presence of maternal antibodies. Here we present a case of a 23-day-old male infant born to primigravida with dengue fever with the post-natal transmission of infection. He presented with complaints of fever for three days. On general examination, red-coloured pinpoint macular rashes were observed bilaterally on lower limbs. No significant findings were present on systemic examination. On routine sepsis workup, thrombocytopenia was present. Acknowledging the endemicity and expanding dengue cases, NS1 antigen and antibody IgM and IgG of the baby were tested which came positive for antigen and IgM antibody. Even so, the mother was asymptomatic with NS1 antigen, IgG and IgM antibodies negative with a normal range of platelet count.
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spelling pubmed-102315462023-06-01 Dengue Fever in a Neonate: A Case Report Bhattarai, Chaitanya Darshan Yadav, Birendra Kumar Basnet, Rabin Karki, Manish Chauhan, Shanta JNMA J Nepal Med Assoc Case Reports Dengue is one of the most common viral infections affecting the general population in endemic areas annually. However, it is barely reported in newborns owing to a widespread belief that they are protected from severe viral infections in the first six months of life by the presence of maternal antibodies. Here we present a case of a 23-day-old male infant born to primigravida with dengue fever with the post-natal transmission of infection. He presented with complaints of fever for three days. On general examination, red-coloured pinpoint macular rashes were observed bilaterally on lower limbs. No significant findings were present on systemic examination. On routine sepsis workup, thrombocytopenia was present. Acknowledging the endemicity and expanding dengue cases, NS1 antigen and antibody IgM and IgG of the baby were tested which came positive for antigen and IgM antibody. Even so, the mother was asymptomatic with NS1 antigen, IgG and IgM antibodies negative with a normal range of platelet count. Journal of the Nepal Medical Association 2023-03 2023-03-31 /pmc/articles/PMC10231546/ /pubmed/37203936 http://dx.doi.org/10.31729/jnma.8099 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Bhattarai, Chaitanya Darshan
Yadav, Birendra Kumar
Basnet, Rabin
Karki, Manish
Chauhan, Shanta
Dengue Fever in a Neonate: A Case Report
title Dengue Fever in a Neonate: A Case Report
title_full Dengue Fever in a Neonate: A Case Report
title_fullStr Dengue Fever in a Neonate: A Case Report
title_full_unstemmed Dengue Fever in a Neonate: A Case Report
title_short Dengue Fever in a Neonate: A Case Report
title_sort dengue fever in a neonate: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231546/
https://www.ncbi.nlm.nih.gov/pubmed/37203936
http://dx.doi.org/10.31729/jnma.8099
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