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A novel home-use culture mechanism for identifying microbial load in urine samples
Diagnosing a urinary tract infection (UTI) is typically a clinical procedure involving multiple steps. The need to perform a test depends on the presence of relevant symptoms. Given the current pandemic situation, visiting a clinic may not be a preferable choice for many users. Many vulnerable group...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231770/ https://www.ncbi.nlm.nih.gov/pubmed/37256899 http://dx.doi.org/10.1371/journal.pone.0285881 |
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author | Singh, Monika Sahai, Riya Pattnaik, Siddharth |
author_facet | Singh, Monika Sahai, Riya Pattnaik, Siddharth |
author_sort | Singh, Monika |
collection | PubMed |
description | Diagnosing a urinary tract infection (UTI) is typically a clinical procedure involving multiple steps. The need to perform a test depends on the presence of relevant symptoms. Given the current pandemic situation, visiting a clinic may not be a preferable choice for many users. Many vulnerable groups of patients, namely, males with certain predispositions and pregnant women, may not present with symptoms of UTI and may go undiagnosed, which could give rise to a more complicated situation. So far, microbial cultures have been used as the gold standard for the diagnosis of an infection. However, performing microbial cultures currently requires trained professionals and laboratory grade equipment. Therefore, there is a need for a home-use culture kit that can serve this purpose. To our knowledge, no such kit exists. Here, we present a feasibility study of an affordable and easy-to-use home-based setup for quantifying bacterial load in a urine. We believe that such a system can be used by people at home to monitor recurrent UTI infections and also by physicians to remotely monitor and prescribe narrow-spectrum antibiotics for more effective treatment. |
format | Online Article Text |
id | pubmed-10231770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-102317702023-06-01 A novel home-use culture mechanism for identifying microbial load in urine samples Singh, Monika Sahai, Riya Pattnaik, Siddharth PLoS One Research Article Diagnosing a urinary tract infection (UTI) is typically a clinical procedure involving multiple steps. The need to perform a test depends on the presence of relevant symptoms. Given the current pandemic situation, visiting a clinic may not be a preferable choice for many users. Many vulnerable groups of patients, namely, males with certain predispositions and pregnant women, may not present with symptoms of UTI and may go undiagnosed, which could give rise to a more complicated situation. So far, microbial cultures have been used as the gold standard for the diagnosis of an infection. However, performing microbial cultures currently requires trained professionals and laboratory grade equipment. Therefore, there is a need for a home-use culture kit that can serve this purpose. To our knowledge, no such kit exists. Here, we present a feasibility study of an affordable and easy-to-use home-based setup for quantifying bacterial load in a urine. We believe that such a system can be used by people at home to monitor recurrent UTI infections and also by physicians to remotely monitor and prescribe narrow-spectrum antibiotics for more effective treatment. Public Library of Science 2023-05-31 /pmc/articles/PMC10231770/ /pubmed/37256899 http://dx.doi.org/10.1371/journal.pone.0285881 Text en © 2023 Singh et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Singh, Monika Sahai, Riya Pattnaik, Siddharth A novel home-use culture mechanism for identifying microbial load in urine samples |
title | A novel home-use culture mechanism for identifying microbial load in urine samples |
title_full | A novel home-use culture mechanism for identifying microbial load in urine samples |
title_fullStr | A novel home-use culture mechanism for identifying microbial load in urine samples |
title_full_unstemmed | A novel home-use culture mechanism for identifying microbial load in urine samples |
title_short | A novel home-use culture mechanism for identifying microbial load in urine samples |
title_sort | novel home-use culture mechanism for identifying microbial load in urine samples |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231770/ https://www.ncbi.nlm.nih.gov/pubmed/37256899 http://dx.doi.org/10.1371/journal.pone.0285881 |
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