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Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast
Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231789/ https://www.ncbi.nlm.nih.gov/pubmed/37200372 http://dx.doi.org/10.1371/journal.pgen.1010691 |