Cargando…

Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast

Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yong-jie, Bhadra, Sankhadip, Mahdi, Alaa Taha A., Dev, Kamal, Yurtsever, Ilknur, Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231789/
https://www.ncbi.nlm.nih.gov/pubmed/37200372
http://dx.doi.org/10.1371/journal.pgen.1010691