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Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast

Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding...

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Detalles Bibliográficos
Autores principales: Xu, Yong-jie, Bhadra, Sankhadip, Mahdi, Alaa Taha A., Dev, Kamal, Yurtsever, Ilknur, Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231789/
https://www.ncbi.nlm.nih.gov/pubmed/37200372
http://dx.doi.org/10.1371/journal.pgen.1010691

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