In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury

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The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ injury including testicular inflammation, reduced testosterone, and germ cell depletion. The ACE2 receptor is also expressed in the resident testicular cells, however, SARS-CoV-2 infection and mechanisms of testicular i...

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Detalles Bibliográficos
Autores principales: Giannakopoulos, Stefanos, Strange, Daniel P., Jiyarom, Boonyanudh, Abdelaal, Omar, Bradshaw, Aaron W., Nerurkar, Vivek R., Ward, Monika A., Bakse, Jackson, Yap, Jonathan, Vanapruks, Selena, Boisvert, William A., Tallquist, Michelle D., Shikuma, Cecilia, Sadri-Ardekani, Hooman, Clapp, Philip, Murphy, Sean V., Verma, Saguna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231791/
https://www.ncbi.nlm.nih.gov/pubmed/37200377
http://dx.doi.org/10.1371/journal.ppat.1011409

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