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2-Deoxy-D-glucose inhibits lymphocytic choriomeningitis virus propagation by targeting glycoprotein N-glycosylation

BACKGROUND: Increased glucose uptake and utilization via aerobic glycolysis are among the most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that similar metabolic changes are also triggered in many virus-infected cells. Viral propagation, like highly proliferative tum...

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Detalles Bibliográficos
Autores principales: Baďurová, Lucia, Polčicová, Katarína, Omasta, Božena, Ovečková, Ingrid, Kocianová, Eva, Tomášková, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231856/
https://www.ncbi.nlm.nih.gov/pubmed/37259080
http://dx.doi.org/10.1186/s12985-023-02082-3