Cargando…

Genotoxic and genoprotective effects of 1,4-dihydropyridine derivatives: a brief review

This review summarises current knowledge about the genotoxic and genoprotective effects of 1,4-dihydropyridines (DHP) with the main focus on the water-soluble 1,4-DHPs. Most of these water-soluble compounds manifest very low calcium channel blocking activity, which is considered “unusual” for 1,4-DH...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leonova, Elina, Ryabokon, Nadezhda, Rostoka, Evita, Borisovs, Vitalijs, Velena, Astrida, Bisenieks, Egils, Duburs, Gunars, Dzintare, Maija, Goncharova, Roza, Sjakste, Nikolajs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231893/ https://www.ncbi.nlm.nih.gov/pubmed/37014687 http://dx.doi.org/10.2478/aiht-2023-74-3707

Ejemplares similares

1,4-dihydropyridine Derivatives Increase mRNA Expression of Psma3, Psmb5, and Psmc6 in Rats
por: Dišlere, Kristīne, et al.
Publicado: (2021)

Spectroscopic and electrochemical study of interactions between DNA and different salts of 1,4-dihydropyridine AV-153
por: Leonova, Elina, et al.
Publicado: (2020)

1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues—Model Compounds Targeting Oxidative Stress
por: Velena, Astrida, et al.
Publicado: (2016)

4-Pyridinio-1,4-Dihydropyridines as Calcium Ion Transport Modulators: Antagonist, Agonist, and Dual Action
por: Domracheva, Ilona, et al.
Publicado: (2020)

Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro
por: Milkovic, Lidija, et al.
Publicado: (2018)

Study of interaction of antimutagenic 1,4-dihydropyridine AV-153-Na with DNA-damaging molecules and its impact on DNA repair activity
por: Leonova, Elina, et al.
Publicado: (2018)

Dihydropyridine Derivatives as Cell Growth Modulators In Vitro
por: Bruvere, Imanta, et al.
Publicado: (2017)

A Review on Genotoxic and Genoprotective Effects of Biologically Active Compounds of Animal Origin
por: Sjakste, Nikolajs, et al.
Publicado: (2023)

The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A
por: Bisenieks, Egils, et al.
Publicado: (2021)

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates
por: Vigante, Brigita, et al.
Publicado: (2015)

Crystal structure and metabolic activity of 4-(thien-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid ethoxycarbonylphenylmethylester
por: Mishnev, Anatoly, et al.
Publicado: (2018)

Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives
por: Petrova, Marina, et al.
Publicado: (2011)

Role of Ocimum sanctum as a Genoprotective Agent on Chlorpyrifos-Induced Genotoxicity
por: Khanna, Asha, et al.
Publicado: (2011)

Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences
por: Sjakste, Tatjana, et al.
Publicado: (2020)

Pleiotropic Properties of Amphiphilic Dihydropyridines, Dihydropyridones, and Aminovinylcarbonyl Compounds
por: Rucins, Martins, et al.
Publicado: (2020)

The Increment of Genoprotective Effect of Melatonin due to "Autooptic" Effect versus the Genotoxicity of Mitoxantrone
por: M., Zamani, et al.
Publicado: (2020)

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines
por: Pajuste, Klavs, et al.
Publicado: (2020)

Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods
por: Zuhra, Karim, et al.
Publicado: (2019)

The Genoprotective Role of Naringin
por: Szczepaniak, Oskar, et al.
Publicado: (2020)

Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives
por: Petrova, M., et al.
Publicado: (2018)

Correction to ‘Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives’
por: Petrova, M., et al.
Publicado: (2018)

Genoprotective Effect of Some Flavonoids against Genotoxic Damage Induced by X-rays In Vivo: Relationship between Structure and Activity
por: Alcaraz, Miguel, et al.
Publicado: (2021)

DNA damage and repair in the differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?
por: Sjakste, Nikolajs, et al.
Publicado: (2021)

Chemistry and personalized medicine – the research and development future of Europe
por: Duburs, Gunars, et al.
Publicado: (2012)

An Intergenic rs9275596 Polymorphism on Chr. 6p21 Is Associated with Multiple Sclerosis in Latvians
por: Paramonova, Natalia, et al.
Publicado: (2020)

Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues
por: Zake, Darta Maija, et al.
Publicado: (2021)

Cytoprotection, Genoprotection, and Dermal Exposure Assessment of Chitosan-Based Agronanofungicides
por: Maluin, Farhatun Najat, et al.
Publicado: (2020)

Metformin mitigates radiation toxicity exerting antioxidant and genoprotective properties
por: Karmanova, Ekaterina E., et al.
Publicado: (2023)

Genetic variations in the PSMA6 and PSMC6 proteasome genes are associated with multiple sclerosis and response to interferon-β therapy in Latvians
por: Paramonova, Natalia, et al.
Publicado: (2021)

Methyl 6-oxo-4-phenyl-2-[(Z)-2-(pyridin-2-yl)ethenyl]-1,4,5,6-tetrahydropyridine-3-carboxylate
por: Smits, Rufus, et al.
Publicado: (2012)

Interaction of Styrylpyridinium Compound with Pathogenic Candida albicans Yeasts and Human Embryonic Kidney HEK-293 Cells
por: Vaitkienė, Simona, et al.
Publicado: (2020)

Evaluation of genoprotection against malathion induced toxicity by Orthosiphon thymiflorus Sleesen
por: Devi R, Seema, et al.
Publicado: (2021)

Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro
por: Jelača, Sanja, et al.
Publicado: (2022)

Rapid but mild genoprotective effect on lymphocytic DNA with Panax notoginseng extract supplementation
por: Szeto, Yim Tong, et al.
Publicado: (2014)

Bauhinia forficata Link, Antioxidant, Genoprotective, and Hypoglycemic Activity in a Murine Model
por: Chávez-Bustos, Erika Anayetzi, et al.
Publicado: (2022)

Development-dependent changes in the tight DNA-protein complexes of barley on chromosome and gene level
por: Sjakste, Tatjana, et al.
Publicado: (2009)

PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese
por: Sjakste, Tatjana, et al.
Publicado: (2014)

A Study of Phytochemistry, Genoprotective Activity, and Antitumor Effects of Extracts of the Selected Lamiaceae Species
por: Oalđe Pavlović, Mariana, et al.
Publicado: (2021)

Genoprotective activity of the Pleurotus eryngii mushrooms following their in vitro and in vivo fermentation by fecal microbiota
por: Boulaka, Athina, et al.
Publicado: (2022)

3-{3,5-Bis[(2-butoxyethoxy)carbonyl]-2,6-dimethyl-1,4-dihydropyridin-4-yl}-1-[(3,4,5-trimethoxybenzoyl)methyl]pyridinium bromide
por: Bisenieks, Imants, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pd5rl9npj0ku3a0qp2afl7llvv