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Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles
The promise of therapeutic nucleic acids has long been tempered by difficulty in overcoming biological barriers to their delivery. The past two decades have seen the development of ionizable lipid nanoparticles as a vehicle for nucleic acid delivery and their translation to the clinic.
Autores principales: | Hamilton, Alex G., Swingle, Kelsey L., Mitchell, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231943/ https://www.ncbi.nlm.nih.gov/pubmed/37093850 http://dx.doi.org/10.1371/journal.pbio.3002105 |
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