Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models

Many patients with hepatocellular carcinoma (HCC) do not respond to the first-line immune checkpoint inhibitor treatment. Immunization with effective cancer vaccines is an attractive alternative approach to immunotherapy. However, its efficacy remains insufficiently evaluated in preclinical studies....

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Detalles Bibliográficos
Autores principales: Lu, Xinjun, Deng, Shanshan, Xu, Jiejie, Green, Benjamin L., Zhang, Honghua, Cui, Guofei, Zhou, Yi, Zhang, Yi, Xu, Hongwei, Zhang, Fapeng, Mao, Rui, Zhong, Sheng, Cramer, Thorsten, Evert, Matthias, Calvisi, Diego F., He, Yukai, Liu, Chao, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231990/
https://www.ncbi.nlm.nih.gov/pubmed/37040183
http://dx.doi.org/10.1172/JCI163291

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