Transcription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy

Renal osteodystrophy (ROD) is a disorder of bone metabolism that affects virtually all patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes including fractures, cardiovascular events, and death. In this study, we showed that hepatocyte nuclear factor 4α (HNF4α)...

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Detalles Bibliográficos
Autores principales: Martinez-Calle, Marta, Courbon, Guillaume, Hunt-Tobey, Bridget, Francis, Connor, Spindler, Jadeah, Wang, Xueyan, dos Reis, Luciene M., Martins, Carolina S.W., Salusky, Isidro B., Malluche, Hartmut, Nickolas, Thomas L., Moyses, Rosa M.A., Martin, Aline, David, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231994/
https://www.ncbi.nlm.nih.gov/pubmed/37079387
http://dx.doi.org/10.1172/JCI159928

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