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Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions...
Autores principales: | Lu, Lina, Wang, Jennifer Rui, Henderson, Ying C., Bai, Shanshan, Yang, Jie, Hu, Min, Shiau, Cheng-Kai, Pan, Timothy, Yan, Yuanqing, Tran, Tuan M., Li, Jianzhuo, Kieser, Rachel, Zhao, Xiao, Wang, Jiping, Nurieva, Roza, Williams, Michelle D., Cabanillas, Maria E., Dadu, Ramona, Busaidy, Naifa Lamki, Zafereo, Mark, Navin, Nicholas, Lai, Stephen Y., Gao, Ruli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231997/ https://www.ncbi.nlm.nih.gov/pubmed/37053016 http://dx.doi.org/10.1172/JCI169653 |
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