IL-6 in the infarcted heart is preferentially formed by fibroblasts and modulated by purinergic signaling

Plasma IL-6 is elevated after myocardial infarction (MI) and is associated with increased morbidity and mortality. Which cardiac cell type preferentially contributes to IL-6 expression and how its production is regulated are largely unknown. Here, we studied the cellular source and purinergic regula...

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Detalles Bibliográficos
Autores principales: Alter, Christina, Henseler, Anne-Sophie, Owenier, Christoph, Hesse, Julia, Ding, Zhaoping, Lautwein, Tobias, Bahr, Jasmin, Hayat, Sikander, Kramann, Rafael, Kostenis, Eva, Scheller, Jürgen, Schrader, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232006/
https://www.ncbi.nlm.nih.gov/pubmed/36943408
http://dx.doi.org/10.1172/JCI163799

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