The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits

Polyglutamine diseases are a group of neurodegenerative disorders caused by an abnormal expansion of CAG repeat tracts in the codifying regions of nine, otherwise unrelated, genes. While the protein products of these genes are suggested to play diverse cellular roles, the pathogenic mutant proteins...

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Detalles Bibliográficos
Autores principales: Koppenol, Rebekah, Conceição, André, Afonso, Inês T, Afonso-Reis, Ricardo, Costa, Rafael G, Tomé, Sandra, Teixeira, Diogo, da Silva, Joana Pinto, Côdesso, José Miguel, Brito, David V C, Mendonça, Liliana, Marcelo, Adriana, Pereira de Almeida, Luís, Matos, Carlos A, Nóbrega, Clévio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232246/
https://www.ncbi.nlm.nih.gov/pubmed/36511898
http://dx.doi.org/10.1093/brain/awac473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232246/
https://www.ncbi.nlm.nih.gov/pubmed/36511898
http://dx.doi.org/10.1093/brain/awac473

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